New approach in asthma treatment using excitatory modulator
Identifieur interne : 001B28 ( Main/Exploration ); précédent : 001B27; suivant : 001B29New approach in asthma treatment using excitatory modulator
Auteurs : Ba X. Hoang [États-Unis] ; D. Graeme Shaw ; Stephen Levine ; Cuong Hoang [Viêt Nam] ; Phuong Pham [États-Unis]Source :
- Phytotherapy Research [ 0951-418X ] ; 2007-06.
English descriptors
- Teeft :
- Active alkaloids, Adverse reactions, Airway, Alkaloid, Allergy, Allergy clin immunol, Asthma, Asthma attacks, Asthma symptoms, Asthma treatment, Avescens, Avescens root, Bronchial asthma, Chronic asthma, Corticosteroid, Corticosteroid inhaler, Daytime asthma symptoms, Daytime symptoms, Diary card, Excitatory modulator, Glutamate, Glutamate receptors, High content, High doses, Hoang allergy research group, Inhaled corticosteroids, John wiley sons, Lidocaine, Matrine, Membrane excitability, Nebulized lidocaine, Nighttime symptoms, Oxymatrine, Pharmacological actions, Pharmacological research, Refractory asthma, Respiratory function, Severe asthma, Side effects, Sodium channels, Sophora, Sophora flavescens, Symptom, Systemic corticosteroids, Therapeutic value, Traditional chinese medicine, Yakugaku zasshi.
Abstract
The impact of a herbal extract with excitatory modulator activity in the management of asthma was studied. An open and selective 3‐year follow‐up of 14 chronic refractory asthmatics aged between 22 and 70 was used. Participants received an extract of Sophora flavescens Ait. Medication use, a diary card of symptoms and respiratory function were recorded. The study was retrospective and all patients gave written informed consent. The quality of life, clinical symptoms and respiratory function improved during all periods of measurement. The use of inhaled corticosteroid and β‐agonists were reduced or eliminated. There were no significant adverse reactions reported. Therefore the extract of S. flavescens as an excitatory modulator appears to be a safe and may be an effective alternative treatment for refractory chronic asthma. Copyright © 2007 John Wiley & Sons, Ltd.
Url:
DOI: 10.1002/ptr.2107
Affiliations:
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An open and selective 3‐year follow‐up of 14 chronic refractory asthmatics aged between 22 and 70 was used. Participants received an extract of Sophora flavescens Ait. Medication use, a diary card of symptoms and respiratory function were recorded. The study was retrospective and all patients gave written informed consent. The quality of life, clinical symptoms and respiratory function improved during all periods of measurement. The use of inhaled corticosteroid and β‐agonists were reduced or eliminated. There were no significant adverse reactions reported. Therefore the extract of S. flavescens as an excitatory modulator appears to be a safe and may be an effective alternative treatment for refractory chronic asthma. Copyright © 2007 John Wiley & Sons, Ltd.</div></front></TEI><affiliations><list><country><li>Viêt Nam</li><li>États-Unis</li></country><region><li>Californie</li></region><settlement><li>Los Angeles</li></settlement><orgName><li>Université de Californie du Sud</li></orgName></list><tree><noCountry><name sortKey="Levine, Stephen" sort="Levine, Stephen" uniqKey="Levine S" first="Stephen" last="Levine">Stephen Levine</name><name sortKey="Shaw, D Graeme" sort="Shaw, D Graeme" uniqKey="Shaw D" first="D. Graeme" last="Shaw">D. Graeme Shaw</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Hoang, Ba X" sort="Hoang, Ba X" uniqKey="Hoang B" first="Ba X." last="Hoang">Ba X. Hoang</name></noRegion><name sortKey="Hoang, Ba X" sort="Hoang, Ba X" uniqKey="Hoang B" first="Ba X." last="Hoang">Ba X. Hoang</name><name sortKey="Pham, Phuong" sort="Pham, Phuong" uniqKey="Pham P" first="Phuong" last="Pham">Phuong Pham</name></country><country name="Viêt Nam"><noRegion><name sortKey="Hoang, Cuong" sort="Hoang, Cuong" uniqKey="Hoang C" first="Cuong" last="Hoang">Cuong Hoang</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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